Cancer Cell Metastasis

Researchers have discovered how cancer cells metastasize or spread from one location to another through the bloodstream. While studying intestinal cancer cells, researchers from the University of Zurich revealed that cancer cells activate receptors in blood vessels that allow them to exit the bloodstream and spread to other organs. The cancer cells release chemical messengers called chemokines that induce an immune response and enable them to pass through the blood vessel into the surrounding area.

According to researcher Lubor Borsig, "CCL2 (chemokine) activates a doorman receptor and enables cancer cells to leave the blood circulation and metastasize in other organs. The mechanism discovered will yield a completely new approach for the development of drugs to combat metastasis in breast, prostate and bowel cancer." The researchers contend that if a method for inhibiting cancer cell chemokine expression could be developed, it would prohibit metastasis by preventing the cells from leaving the bloodstream.

Learn more about this study:

Source: http://biology.about.com/b/2012/07/12/cancer-cell-metastasis.htm

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